ABSTRACT
OBJECTIVE@#To investigate ultrastructural pathological changes of Heroin-Addicts.@*METHODS@#Heroin-Addicts' central nervous system, endocrine system, immune system and reproductive system in 4 cases are observed by using transmission electron microscope(TEM).@*RESULTS@#The changes of central nervous system are mitochondrion swelling, crista fragmentation and disappear. Endoplasmic reticulum dilation, nervous fibres and cell organelles reduction; mitochondrion swelling, Partial crista fragmentation and endoplasmic reticulum dilation are also found in endocrine system; Lymphocytes reduction, cytoplasm ingredient reduction and dead lymphocytes increase in immune system; in reproductive system, spermatogenic cells and cell organelles are reduced in the male and follicle disappeared in the female.@*CONCLUSION@#Ultra-structural pathological changes of heroin-addicts are presented acute, chronic oxygen deficiency degeneration and necrosis.
Subject(s)
Female , Humans , Male , Central Nervous System/ultrastructure , Endocrine System/ultrastructure , Genitalia/ultrastructure , Heroin Dependence/pathology , Immune System/ultrastructure , Microscopy, ElectronABSTRACT
Triatoma brasiliens is considered one of the most important Chagas disease vectors being a wide-spread species in semiarid areas of northeastern Brazil. The species displays distinct chromatic pattern of the cutile in different localities. Four populations were analysed in this study: 1-Caico, Rio Grande do Norte, it will be called the brasiliensis population; 2-Espinosa, Minas Gerais, the melanica population; 3-Petrolina, Pernambuco, the macromelasoma population, and 4-Juazeiro, Bahia, the darker one in overall cutile coloration, the Juazeiro population. In order to differentiate the four populations of T. brasiliensis, a comparative morphological analysis of external genital structures and of eggs were carried out. The analysis of the male genital structures evidenced minor individual stuctural variations that did not correlate with chromatic differences or the geographical origins, emphasizing the importance of examining sufficiently large and representative samples before using minor genital variations for taxonomic diagnosis. By scanning electron microscopy of the egg exochorion, each chromatic population presented a distinct ornamentation pattern. The melancia population differed mainly from the other populations studied since it had about 40.6 per cent, 69.6 per cent and 76.6 per cent more perforations, on each cell exochorion, than the brasiliensis, the Juazeiro and the macromelasoma populations respectively. In the melancia population the perforation layout is also peculiar, with densely distributed perforations over all the egg surface. Morphometric measures of the eggs showed statistically significant differences: the macromelasoma population presented the longest length (2.43 mm) while the shortest was recorded in the brasiliensis population (2.29 mm).
Subject(s)
Animals , Genitalia/ultrastructure , Ovum/ultrastructure , Triatoma/ultrastructure , Microscopy, Electron, Scanning/instrumentationABSTRACT
Las alteraciones morfológicas de la glándula de coagulación de las ratas vasectomizadas, fueron observadas utilizando microscopía de luz y microscopía electrónica de transmisión. Los resultados demostraron disminución en la altura del epitelio secretor. Observaciones ultraestructurales mostraron atrofia de las cisternas del retículo endoplasmático granular